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Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin

Fusobacterium nucleatum (Fn) has been associated with colorectal cancer (CRC), but causality and underlying mechanisms remain to be established. We demonstrate that Fn adheres to, invades and induces oncogenic and inflammatory responses to stimulate growth of CRC cells through its unique FadA adhesi...

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Bibliografiske detaljer
Main Authors: Rubinstein, Mara Roxana, Wang, Xiaowei, Liu, Wendy, Hao, Yujun, Cai, Guifang, Han, Yiping W.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770529/
https://ncbi.nlm.nih.gov/pubmed/23954158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.07.012
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