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Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are chronic inflammatory demyelinating and neurodegenerative diseases of the CNS. Although neurodegeneration is the major contributor to chronic disability in MS, mechanisms governing the viability of axon...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Stone, Sarrabeth, Yue, Yuan, Stanojlovic, Milos, Wu, Shuangchan, Karsenty, Gerard, Lin, Wensheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413796/
https://ncbi.nlm.nih.gov/pubmed/30674717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124232
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