Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis

Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are chronic inflammatory demyelinating and neurodegenerative diseases of the CNS. Although neurodegeneration is the major contributor to chronic disability in MS, mechanisms governing the viability of axon...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Stone, Sarrabeth, Yue, Yuan, Stanojlovic, Milos, Wu, Shuangchan, Karsenty, Gerard, Lin, Wensheng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413796/
https://ncbi.nlm.nih.gov/pubmed/30674717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124232
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