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Neuron-specific PERK inactivation exacerbates neurodegeneration during experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), are chronic inflammatory demyelinating and neurodegenerative diseases of the CNS. Although neurodegeneration is the major contributor to chronic disability in MS, mechanisms governing the viability of axon...
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| Publicado no: | JCI Insight |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413796/ https://ncbi.nlm.nih.gov/pubmed/30674717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.124232 |
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