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PKC epsilon signaling effect on actin assembly is diminished in cardiomyocytes when challenged to additional work in a stiff microenvironment

The stiffness of the microenvironment surrounding a cell can result in cytoskeletal remodeling, leading to altered cell function and tissue macrostructure. In this study, we tuned the stiffness of the underlying substratum on which neonatal rat cardiomyocytes were grown in culture in order to mimic...

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Detalhes bibliográficos
Publicado no:Cytoskeleton (Hoboken)
Main Authors: Mkrtschjan, Michael A., Solís, Christopher, Wondmagegn, Admasu Y., Majithia, Janki, Russell, Brenda
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413695/
https://ncbi.nlm.nih.gov/pubmed/30019430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21472
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