Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months

BACKGROUND: Behaviour problems are prevalent among children born very preterm (≤ 32 weeks gestation), and have been associated with morphine exposure. Morphine accumulation in the brain is determined by genetic variations related to morphine biotransformation. The objective of the study was to inves...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Chau, Cecil M.Y., Ross, Colin J.D., Chau, Vann, Synnes, Anne R., Miller, Steven P., Carleton, Bruce, Grunau, Ruth E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413679/
https://ncbi.nlm.nih.gov/pubmed/30709768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.042
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