Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months

BACKGROUND: Behaviour problems are prevalent among children born very preterm (≤ 32 weeks gestation), and have been associated with morphine exposure. Morphine accumulation in the brain is determined by genetic variations related to morphine biotransformation. The objective of the study was to inves...

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Enregistré dans:
Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Chau, Cecil M.Y., Ross, Colin J.D., Chau, Vann, Synnes, Anne R., Miller, Steven P., Carleton, Bruce, Grunau, Ruth E.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Research paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413679/
https://ncbi.nlm.nih.gov/pubmed/30709768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.042
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