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Morphine biotransformation genes and neonatal clinical factors predicted behaviour problems in very preterm children at 18 months

BACKGROUND: Behaviour problems are prevalent among children born very preterm (≤ 32 weeks gestation), and have been associated with morphine exposure. Morphine accumulation in the brain is determined by genetic variations related to morphine biotransformation. The objective of the study was to inves...

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Bibliographic Details
Published in:EBioMedicine
Main Authors: Chau, Cecil M.Y., Ross, Colin J.D., Chau, Vann, Synnes, Anne R., Miller, Steven P., Carleton, Bruce, Grunau, Ruth E.
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413679/
https://ncbi.nlm.nih.gov/pubmed/30709768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.01.042
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