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Replacement of Stoichiometric DDQ with a Low Potential o-Quinone Catalyst Enabling Aerobic Dehydrogenation of Tertiary Indolines in Pharmaceutical Intermediates

A transition-metal/quinone complex, [Ru(phd)(3)](2+) (phd = 1,10-phenanthroline-5,6-dione), is shown to be effective for aerobic dehydrogenation of 3° indolines to the corresponding indoles. The results show how low potential quinones may be tailored to provide a catalytic alternative to stoichiomet...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Li, Bao, Wendlandt, Alison E., Stahl, Shannon S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413530/
https://ncbi.nlm.nih.gov/pubmed/30702297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b00111
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