Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

The transplantation of pancreatic islet cells could restore glycaemic control in patients with type-I diabetes. Microspheres for islet encapsulation have enabled long-term glycaemic control in diabetic rodent models; yet human patients transplanted with equivalent microsphere formulations have exper...

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Publicat a:Nat Biomed Eng
Autors principals: Bochenek, Matthew A., Veiseh, Omid, Vegas, Arturo J., McGarrigle, James J., Qi, Meirigeng, Marchese, Enza, Omami, Mustafa, Doloff, Joshua C., Mendoza-Elias, Joshua, Nourmohammadzadeh, Mohammad, Khan, Arshad, Yeh, Chun-Chieh, Xing, Yuan, Isa, Douglas, Ghani, Sofia, Li, Jie, Landry, Casey, Bader, Andrew R., Olejnik, Karsten, Chen, Michael, Hollister-Lock, Jennifer, Wang, Yong, Greiner, Dale L., Weir, Gordon C., Løkensgard Strand, Berit, Rokstad, Anne Mari A., Lacik, Igor, Langer, Robert, Anderson, Daniel G., Oberholzer, Jose
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413527/
https://ncbi.nlm.nih.gov/pubmed/30873298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-018-0275-1
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