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A Clinically Applicable Positive Allosteric Modulator of GABA Receptors Promotes Human β-Cell Replication and Survival as well as GABA's Ability to Inhibit Inflammatory T Cells

A major goal of T1D research is to develop new approaches to increase β-cell mass and control autoreactive T cell responses. GABA(A)-receptors (GABA(A)-Rs) are promising drug targets in both those regards due to their abilities to promote β-cell replication and survival, as well as inhibit autoreact...

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Detalhes bibliográficos
Publicado no:J Diabetes Res
Main Authors: Tian, Jide, Dang, Hoa, Karashchuk, Nataliya, Xu, Irvin, Kaufman, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413367/
https://ncbi.nlm.nih.gov/pubmed/30937314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/5783545
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