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Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication. A number of positive allosteric modulators (PAMs)...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5428733/ https://ncbi.nlm.nih.gov/pubmed/28336918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-00515-y |
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