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Proton countertransport and Coupled gating in the sarcoplasmic reticulum calcium pump
The calcium pump of the sarcoplasmic reticulum (SERCA) is an ATP-driven active transporter of Ca(2+) ions that functions via an “alternating-access” cycle mechanism. In each cycle, SERCA transports two Ca(2+) ions toward the lumen of the sarcoplasmic reticulum, and 2–3 protons to the cytoplasm. How...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6413324/ https://ncbi.nlm.nih.gov/pubmed/30539761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2018.10.014 |
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