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Mechanism of inhibition of the calcium pump of sarcoplasmic reticulum by thapsigargin.

The steady-state ATPase activity of sarcoplasmic-reticulum (Ca(2+)-Mg2+)-ATPase is inhibited by thapsigargin at a molar ratio of 1:1, with a dissociation constant for thapsigargin estimated to be in the sub-nanomolar range. In the presence of thapsigargin, only a single Ca2+ ion binds to the ATPase....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wictome, M, Henderson, I, Lee, A G, East, J M
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 1992
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1131067/
https://ncbi.nlm.nih.gov/pubmed/1533513
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