JQ1 effectively inhibits vasculogenic mimicry of pancreatic ductal adenocarcinoma cells via the ERK1/2-MMP-2/9 signaling pathway both in vitro and in vivo

Vasculogenic mimicry (VM) is an alternative type of blood and nutrition supply that is associated with more aggressive tumor biology and increased cancer-related mortality. However, the clinical implications of VM remain unclear in patients with pancreatic ductal adenocarcinoma (PDAC). The aim of th...

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Veröffentlicht in:Am J Transl Res
Hauptverfasser: Zhuo, Meng, Yuan, Cuncun, Han, Ting, Hu, Hai, Cui, Jiujie, Jiao, Feng, Wang, Liwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6413294/
https://ncbi.nlm.nih.gov/pubmed/30899402
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