Rictor regulates the vasculogenic mimicry of melanoma via the AKT‐MMP‐2/9 pathway

Vasculogenic mimicry (VM)‐positive melanomas are usually associated with poor prognosis. Rictor, the key component of the rapamycin‐insensitive complex of mTOR (mTORC2), is up‐regulated in several cancers, especially in melanomas with poor prognosis. The aim of this study was to investigate the role...

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Publicado en:J Cell Mol Med
Autores principales: Liang, Xingmei, Sun, Ran, Zhao, Xiulan, Zhang, Yanhui, Gu, Qiang, Dong, Xueyi, Zhang, Danfang, Sun, Junying, Sun, Baocun
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2017
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706568/
https://ncbi.nlm.nih.gov/pubmed/28699701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13268
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