Rictor regulates the vasculogenic mimicry of melanoma via the AKT‐MMP‐2/9 pathway

Vasculogenic mimicry (VM)‐positive melanomas are usually associated with poor prognosis. Rictor, the key component of the rapamycin‐insensitive complex of mTOR (mTORC2), is up‐regulated in several cancers, especially in melanomas with poor prognosis. The aim of this study was to investigate the role...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Liang, Xingmei, Sun, Ran, Zhao, Xiulan, Zhang, Yanhui, Gu, Qiang, Dong, Xueyi, Zhang, Danfang, Sun, Junying, Sun, Baocun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5706568/
https://ncbi.nlm.nih.gov/pubmed/28699701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13268
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