(−)-Oleocanthal Combined with Lapatinib Treatment Synergized against HER-2 Positive Breast Cancer In Vitro and In Vivo

Dysregulation of epidermal growth factor receptor (EGFR)/human epidermal growth factor-2 (HER2) family is a hallmark of aggressive breast cancer. Small-molecule tyrosine kinase inhibitors are among the most effective cancer targeted treatments. (−)-Oleocanthal (OC) is a naturally occurring phenolic...

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Vydáno v:Nutrients
Hlavní autoři: Siddique, Abu Bakar, Ebrahim, Hassan Y., Akl, Mohamed R., Ayoub, Nehad M., Goda, Amira A., Mohyeldin, Mohamed M., Nagumalli, Suresh K., Hananeh, Wael M., Liu, Yong-Yu, Meyer, Sharon A., El Sayed, Khalid A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412724/
https://ncbi.nlm.nih.gov/pubmed/30781364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11020412
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