Olive Phenolics as c-Met Inhibitors: (-)-Oleocanthal Attenuates Cell Proliferation, Invasiveness, and Tumor Growth in Breast Cancer Models

Dysregulation of the Hepatocyte growth factor (HGF)/c-Met signaling axis upregulates diverse tumor cell functions, including cell proliferation, survival, scattering and motility, epithelial-to-mesenchymal transition (EMT), angiogenesis, invasion, and metastasis. (-)-Oleocanthal is a naturally occur...

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Detalhes bibliográficos
Main Authors: Akl, Mohamed R., Ayoub, Nehad M., Mohyeldin, Mohamed M., Busnena, Belnaser A., Foudah, Ahmed I., Liu, Yong-Yu, Sayed, Khalid A. EI
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029740/
https://ncbi.nlm.nih.gov/pubmed/24849787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097622
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