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Botulinum Neurotoxin-A Injected Intrastriatally into Hemiparkinsonian Rats Improves the Initiation Time for Left and Right Forelimbs in Both Forehand and Backhand Directions

Forelimb stepping is a widely used test for the assessment of forelimb akinesia in hemiparkinsonian (hemi-PD) rats. The initiation time (IT) is considered the most sensitive parameter in the stepping test procedure. Here we propose a novel, reliable, and simple method for the measurement of IT of bo...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Antipova, Veronica, Holzmann, Carsten, Hawlitschka, Alexander, Wree, Andreas
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412467/
https://ncbi.nlm.nih.gov/pubmed/30823527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20040992
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