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Repeated Intrastriatal Botulinum Neurotoxin-A Injection in Hemiparkinsonian Rats Increased the Beneficial Effect on Rotational Behavior

Injection of botulinum neurotoxin-A (BoNT-A) into the striatum of hemiparkinsonian (hemi-PD) rats reduced apomorphine-induced rotation behavior significantly, for at least 3 months. Thereafter, rotation behavior increased again. We injected hemi-PD rats with 1 ng BoNT-A twice, the second injection f...

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發表在:Toxins (Basel)
Main Authors: Hawlitschka, Alexander, Holzmann, Carsten, Wree, Andreas, Antipova, Veronica
格式: Artigo
語言:Inglês
出版: MDPI 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162461/
https://ncbi.nlm.nih.gov/pubmed/30208596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins10090368
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