CCNA2 Ablation in Aged Mice Results in Abnormal rRNA Granule Accumulation in Hippocampus

Mounting evidence in the literature suggests that RNA–RNA binding protein aggregations can disturb neuronal homeostasis and lead to symptoms associated with normal aging as well as dementia. The specific ablation of cyclin A2 in adult neurons results in neuronal polyribosome aggregations and learnin...

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Detaylı Bibliyografya
Yayımlandı:Am J Pathol
Asıl Yazarlar: Alves, Michele J., Goksel, Mustafa, Kaya, Behiye, Mostafa, Hasnaa, Gygli, Patrick, Stephens, Julie, Fair, Summer, Otero, José J., Czeisler, Catherine M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Investigative Pathology 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412465/
https://ncbi.nlm.nih.gov/pubmed/30579783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.10.020
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