Blocking NF-κB Activation in Ly6c(+) Monocytes Attenuates Necrotizing Enterocolitis

Necrotizing enterocolitis (NEC) is a devastating disease affecting premature infants with intestinal inflammation and necrosis. The neonatal intestinal inflammatory response is rich in macrophages, and blood monocyte count is low in human NEC. We previously found that NF-κB mediates the intestinal i...

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Publicat a:Am J Pathol
Autors principals: Managlia, Elizabeth, Liu, Shirley X.L., Yan, Xiaocai, Tan, Xiao-Di, Chou, Pauline M., Barrett, Terrence A., De Plaen, Isabelle G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412404/
https://ncbi.nlm.nih.gov/pubmed/30593820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.11.015
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