Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice

The pathogenesis of necrotizing enterocolitis (NEC), a common gastrointestinal disease affecting premature infants, remains poorly understood. We previously found that intestinal VEGF-A expression is decreased in human NEC samples and in a neonatal mouse NEC model prior to detectable histological in...

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Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Yan, Xiaocai, Managlia, Elizabeth, Liu, Shirley XL, Tan, Xiao-Di, Wang, Xiao, Marek, Catherine, De Plaen, Isabelle G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
Matèries:
Translational Physiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867326/
https://ncbi.nlm.nih.gov/pubmed/26950855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00273.2015
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