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Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice

The pathogenesis of necrotizing enterocolitis (NEC), a common gastrointestinal disease affecting premature infants, remains poorly understood. We previously found that intestinal VEGF-A expression is decreased in human NEC samples and in a neonatal mouse NEC model prior to detectable histological in...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Yan, Xiaocai, Managlia, Elizabeth, Liu, Shirley XL, Tan, Xiao-Di, Wang, Xiao, Marek, Catherine, De Plaen, Isabelle G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4867326/
https://ncbi.nlm.nih.gov/pubmed/26950855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00273.2015
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