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Multicharged Phthalocyanines as Selective Ligands for G-Quadruplex DNA Structures

The stabilization of G-Quadruplex DNA structures by ligands is a promising strategy for telomerase inhibition in cancer therapy since this enzyme is responsible for the unlimited proliferation of cancer cells. To assess the potential of a compound as a telomerase inhibitor, selectivity for quadruple...

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Bibliografski detalji
Izdano u:Molecules
Glavni autori: Ramos, Catarina I. V., Almeida, Susana P., Lourenço, Leandro M. O., Pereira, Patrícia M. R., Fernandes, Rosa, Faustino, M. Amparo F., Tomé, João P. C., Carvalho, Josué, Cruz, Carla, Neves, M. Graça P. M. S.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412362/
https://ncbi.nlm.nih.gov/pubmed/30781675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24040733
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