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Allogeneic ADSCs induce CD8 T cell-mediated cytotoxicity and faster cell death after exposure to xenogeneic serum or proinflammatory cytokines

This study examined the induction of recipient T-cell cytotoxicity after exposure to allogeneic adipose-derived mesenchymal stem cells (ADSCs). ADSCs pre-exposed to xenogeneic serum significantly induced cytotoxicity through CD8 T-cell granzyme B secretion after allogeneic antigen stimulation, and t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Exp Mol Med
Main Authors: Chang, Sung-Ho, Park, Chung-Gyu
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6412000/
https://ncbi.nlm.nih.gov/pubmed/30858365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-019-0231-5
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