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Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture

Human pancreatic exocrine cells were cultured in 3D suspension and formed pancreatospheres composed of acinar-derived and duct-like cells. We investigated, up to 6 days, the fate of human pancreatic acinar cells using fluorescein-conjugated Ulex Europaeus Agglutinin 1 lectin, a previously published...

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Vydáno v:Sci Rep
Hlavní autoři: Baldan, Jonathan, Houbracken, Isabelle, Rooman, Ilse, Bouwens, Luc
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411888/
https://ncbi.nlm.nih.gov/pubmed/30858455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40481-1
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