Low-dose 2-deoxyglucose and metformin synergically inhibit proliferation of human polycystic kidney cells by modulating glucose metabolism

Polycystic kidney disease (PKD) is a common hereditary kidney disease with abnormal proliferation and apoptosis of kidney cystic epithelial cells, eventually leading to chronic renal failure. Currently, there are no effective treatment methods. Similar to tumor cells, cystic epithelial cells have ab...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Discov
Main Authors: Zhao, Jing, Ma, Yuxiang, Zhang, Yingjie, Fu, Bo, Wu, Xiaoyuan, Li, Qinggang, Cai, Guangyan, Chen, Xiangmei, Bai, Xue-Yuan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411866/
https://ncbi.nlm.nih.gov/pubmed/30886744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0156-8
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki