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Use of machine learning to identify novel, behaviorally active antagonists of the insect odorant receptor co-receptor (Orco) subunit

Olfaction is a key component of the multimodal approach used by mosquitoes to target and feed on humans, spreading various diseases. Current repellents have drawbacks, necessitating development of more effective agents. In addition to variable odorant specificity subunits, all insect odorant recepto...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Kepchia, Devin, Xu, Pingxi, Terryn, Raymond, Castro, Ana, Schürer, Stephan C., Leal, Walter S., Luetje, Charles W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411751/
https://ncbi.nlm.nih.gov/pubmed/30858563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40640-4
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