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Use of machine learning to identify novel, behaviorally active antagonists of the insect odorant receptor co-receptor (Orco) subunit

Olfaction is a key component of the multimodal approach used by mosquitoes to target and feed on humans, spreading various diseases. Current repellents have drawbacks, necessitating development of more effective agents. In addition to variable odorant specificity subunits, all insect odorant recepto...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Kepchia, Devin, Xu, Pingxi, Terryn, Raymond, Castro, Ana, Schürer, Stephan C., Leal, Walter S., Luetje, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411751/
https://ncbi.nlm.nih.gov/pubmed/30858563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40640-4
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