Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter

Stem cell therapy has great prospects for brain white matter disorders, including the genetically determined disorders called leukodystrophies. We focus on the devastating leukodystrophy vanishing white matter (VWM). Patients with VWM show severe disability and early death, and treatment options are...

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Pubblicato in:Stem Cell Reports
Autori principali: Dooves, Stephanie, Leferink, Prisca S., Krabbenborg, Sander, Breeuwsma, Nicole, Bots, Saskia, Hillen, Anne E.J., Jacobs, Gerbren, van der Knaap, Marjo S., Heine, Vivi M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Report
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411482/
https://ncbi.nlm.nih.gov/pubmed/30799272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.01.018
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