Cell Replacement Therapy Improves Pathological Hallmarks in a Mouse Model of Leukodystrophy Vanishing White Matter

Stem cell therapy has great prospects for brain white matter disorders, including the genetically determined disorders called leukodystrophies. We focus on the devastating leukodystrophy vanishing white matter (VWM). Patients with VWM show severe disability and early death, and treatment options are...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Dooves, Stephanie, Leferink, Prisca S., Krabbenborg, Sander, Breeuwsma, Nicole, Bots, Saskia, Hillen, Anne E.J., Jacobs, Gerbren, van der Knaap, Marjo S., Heine, Vivi M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411482/
https://ncbi.nlm.nih.gov/pubmed/30799272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.01.018
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