Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

OBJECTIVE: Cancer-associated fibroblasts (CAFs) play an important role in the progression of pancreatic ductal adenocarcinoma (PDAC) by promoting tumor cell migration and drug resistance. We determined the impact of CAFs on PDAC cancer stem cells (CSCs). METHODS: Fibroblast cell lines from patients’...

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發表在:Pancreas
Main Authors: Begum, Asma, McMillan, Ross H., Chang, Yu-Tai, Penchev, Vesselin R., N.V., Rajeshkumar, Maitra, Anirban, Goggins, Michael G., Eshelman, James R., Wolfgang, Christopher L., Rasheed, Zeshaan A., Matsui, William
格式: Artigo
語言:Inglês
出版: 2019
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411432/
https://ncbi.nlm.nih.gov/pubmed/30747824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001249
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