Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

OBJECTIVE: Cancer-associated fibroblasts (CAFs) play an important role in the progression of pancreatic ductal adenocarcinoma (PDAC) by promoting tumor cell migration and drug resistance. We determined the impact of CAFs on PDAC cancer stem cells (CSCs). METHODS: Fibroblast cell lines from patients’...

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Publicado en:Pancreas
Main Authors: Begum, Asma, McMillan, Ross H., Chang, Yu-Tai, Penchev, Vesselin R., N.V., Rajeshkumar, Maitra, Anirban, Goggins, Michael G., Eshelman, James R., Wolfgang, Christopher L., Rasheed, Zeshaan A., Matsui, William
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411432/
https://ncbi.nlm.nih.gov/pubmed/30747824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001249
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