Direct Interactions With Cancer-Associated Fibroblasts Lead to Enhanced Pancreatic Cancer Stem Cell Function

OBJECTIVE: Cancer-associated fibroblasts (CAFs) play an important role in the progression of pancreatic ductal adenocarcinoma (PDAC) by promoting tumor cell migration and drug resistance. We determined the impact of CAFs on PDAC cancer stem cells (CSCs). METHODS: Fibroblast cell lines from patients’...

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Publicat a:Pancreas
Autors principals: Begum, Asma, McMillan, Ross H., Chang, Yu-Tai, Penchev, Vesselin R., N.V., Rajeshkumar, Maitra, Anirban, Goggins, Michael G., Eshelman, James R., Wolfgang, Christopher L., Rasheed, Zeshaan A., Matsui, William
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411432/
https://ncbi.nlm.nih.gov/pubmed/30747824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000001249
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