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An Antiviral Branch of the IL-1 Signaling Pathway Restricts Immune-Evasive Virus Replication

Virulent pathogens often cause the release of host-derived damage-associated molecular patterns (DAMPs) from infected cells. During encounters with immune-evasive viruses that block inflammatory gene expression, preformed DAMPs provide backup inflammatory signals that ensure protective immunity. Whe...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Orzalli, Megan H., Smith, Avi, Jurado, Kellie A., Iwasaki, Akiko, Garlick, Jonathan A., Kagan, Jonathan C.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411291/
https://ncbi.nlm.nih.gov/pubmed/30100266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.07.009
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