Plasmodium-specific antibodies block in vivo parasite growth without clearing infected red blood cells

Plasmodium parasites invade and multiply inside red blood cells (RBC). Through a cycle of maturation, asexual replication, rupture and release of multiple infective merozoites, parasitised RBC (pRBC) can reach very high numbers in vivo, a process that correlates with disease severity in humans and e...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Akter, Jasmin, Khoury, David S., Aogo, Rosemary, Lansink, Lianne I. M., SheelaNair, Arya, Thomas, Bryce S., Laohamonthonkul, Pawat, Pernold, Clara P. S., Dixon, Matthew W. A., Soon, Megan S. F., Fogg, Lily G., Engel, Jessica A., Elliott, Trish, Sebina, Ismail, James, Kylie R., Cromer, Deborah, Davenport, Miles P., Haque, Ashraful
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6411214/
https://ncbi.nlm.nih.gov/pubmed/30811498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007599
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