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Effect of Mature Blood-Stage Plasmodium Parasite Sequestration on Pathogen Biomass in Mathematical and In Vivo Models of Malaria

Parasite biomass and microvasculature obstruction are strongly associated with disease severity and death in Plasmodium falciparum-infected humans. This is related to sequestration of mature, blood-stage parasites (schizonts) in peripheral tissue. The prevailing view is that schizont sequestration l...

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Bibliografiska uppgifter
Huvudupphovsmän: Khoury, David S., Cromer, Deborah, Best, Shannon E., James, Kylie R., Kim, Peter S., Engwerda, Christian R., Haque, Ashraful, Davenport, Miles P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911827/
https://ncbi.nlm.nih.gov/pubmed/24144725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00705-13
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