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Effect of Mature Blood-Stage Plasmodium Parasite Sequestration on Pathogen Biomass in Mathematical and In Vivo Models of Malaria

Parasite biomass and microvasculature obstruction are strongly associated with disease severity and death in Plasmodium falciparum-infected humans. This is related to sequestration of mature, blood-stage parasites (schizonts) in peripheral tissue. The prevailing view is that schizont sequestration l...

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主要な著者: Khoury, David S., Cromer, Deborah, Best, Shannon E., James, Kylie R., Kim, Peter S., Engwerda, Christian R., Haque, Ashraful, Davenport, Miles P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2014
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911827/
https://ncbi.nlm.nih.gov/pubmed/24144725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00705-13
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