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Development of a high-throughput fluorescent no-wash sodium influx assay
Voltage-gated sodium channels (Na(V)s) are key therapeutic targets for pain, epilepsy and cardiac arrhythmias. Here we describe the development of a no-wash fluorescent sodium influx assay suitable for high-throughput screening and characterization of novel drug leads. Addition of red-violet food dy...
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| Pubblicato in: | PLoS One |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6411159/ https://ncbi.nlm.nih.gov/pubmed/30856233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0213751 |
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