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Mechanistic Investigation of the Androgen Receptor DNA-Binding Domain Inhibitor Pyrvinium
[Image: see text] Pyrvinium was identified as the first small molecule inhibitor of the androgen receptor (AR) DNA-binding domain (DBD). It was also among the first small molecules shown to directly inhibit the activity of AR splice variants (ARVs), which has important clinical implications in the t...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6410682/ https://ncbi.nlm.nih.gov/pubmed/30873507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03205 |
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