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Respective contributions of single and compound granule fusion to secretion by activated platelets

Although granule secretion is pivotal in many platelet responses, the fusion routes of α and δ granule release remain uncertain. We used a 3D reconstruction approach based on electron microscopy to visualize the spatial organization of granules in unstimulated and activated platelets. Two modes of e...

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Dettagli Bibliografici
Pubblicato in:Blood
Autori principali: Eckly, Anita, Rinckel, Jean-Yves, Proamer, Fabienne, Ulas, Neslihan, Joshi, Smita, Whiteheart, Sidney W., Gachet, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410540/
https://ncbi.nlm.nih.gov/pubmed/27625359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-03-705681
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