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Isolation, Structure Elucidation and Biological Evaluation of Lagunamide D: A New Cytotoxic Macrocyclic Depsipeptide from Marine Cyanobacteria

Lagunamide D, a new cytotoxic macrocyclic depsipeptide, was discovered from a collection of marine cyanobacteria from Loggerhead Key in the Dry Tortugas, Florida. An intramolecular ester exchange was observed, where the 26-membered macrocycle could contract to a 24-membered compound via acyl migrati...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Luo, Danmeng, Putra, Masteria Y., Ye, Tao, Paul, Valerie J., Luesch, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410412/
https://ncbi.nlm.nih.gov/pubmed/30717076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17020083
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