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The Histone-Deacetylase-Inhibitor Suberoylanilide Hydroxamic Acid Promotes Dental Pulp Repair Mechanisms Through Modulation of Matrix Metalloproteinase-13 Activity

Direct application of histone-deacetylase-inhibitors (HDACis) to dental pulp cells (DPCs) induces chromatin changes, promoting gene expression and cellular-reparative events. We have previously demonstrated that HDACis (valproic acid, trichostatin A) increase mineralization in dental papillae-derive...

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Detalhes bibliográficos
Publicado no:J Cell Physiol
Main Authors: DUNCAN, HENRY F., SMITH, ANTHONY J., FLEMING, GARRY J. P., PARTRIDGE, NICOLA C., SHIMIZU, EMI, MORAN, GARY P., COOPER, PAUL R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6410376/
https://ncbi.nlm.nih.gov/pubmed/26264761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25128
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