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Development and Application of Immunoaffinity Column Purification and Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry for Determination of Domoic Acid in Shellfish

Domoic acid (DA) is a neurotoxin associated with amnesic shellfish poisoning (ASP). Though LC coupled to tandem mass spectrometry (LC-MS/MS) has become the preferred method for DA determination, traditional sample pretreatment is still labor-intensive. In this study, a simple, efficient and selectiv...

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Detalhes bibliográficos
Publicado no:Toxins (Basel)
Main Authors: Chen, Si, Zhang, Xiaojun, Yan, Zhongyong, Hu, Yangyang, Lu, Yibo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409838/
https://ncbi.nlm.nih.gov/pubmed/30717167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11020083
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