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The Cancer Aneuploidy Paradox: In the Light of Evolution
Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two pare...
Shranjeno v:
| izdano v: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409809/ https://ncbi.nlm.nih.gov/pubmed/30691027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020083 |
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