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The Cancer Aneuploidy Paradox: In the Light of Evolution
Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two pare...
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| 出版年: | Genes (Basel) |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409809/ https://ncbi.nlm.nih.gov/pubmed/30691027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020083 |
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