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The Cancer Aneuploidy Paradox: In the Light of Evolution
Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two pare...
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| Publicado no: | Genes (Basel) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6409809/ https://ncbi.nlm.nih.gov/pubmed/30691027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10020083 |
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