Methotrexate-Loaded Solid Lipid Nanoparticles: Protein Functionalization to Improve Brain Biodistribution

Glioblastoma is the most common and invasive primary tumor of the central nervous system and normally has a negative prognosis. Biodistribution in healthy animal models is an important preliminary study aimed at investigating the efficacy of chemotherapy, as it is mainly addressed towards residual c...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Muntoni, Elisabetta, Martina, Katia, Marini, Elisabetta, Giorgis, Marta, Lazzarato, Loretta, Salaroglio, Iris Chiara, Riganti, Chiara, Lanotte, Michele, Battaglia, Luigi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409770/
https://ncbi.nlm.nih.gov/pubmed/30717376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11020065
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