The Impact of MGMT Promoter Methylation and Temozolomide Treatment in Serbian Patients with Primary Glioblastoma

Background and objective: Despite recent advances in treatment, glioblastoma (GBM) remains the most lethal and aggressive brain tumor. A continuous search for a reliable molecular marker establishes the methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter as a key pr...

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Detalhes bibliográficos
Publicado no:Medicina (Kaunas)
Main Authors: Jovanović, Nikola, Mitrović, Tatjana, Cvetković, Vladimir J., Tošić, Svetlana, Vitorović, Jelena, Stamenković, Slaviša, Nikolov, Vesna, Kostić, Aleksandar, Vidović, Nataša, Krstić, Miljan, Jevtović-Stoimenov, Tatjana, Pavlović, Dušica
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409652/
https://ncbi.nlm.nih.gov/pubmed/30717206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicina55020034
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