Pharmacogenetics may Influence Tacrolimus Daily Dose, but not Urinary Tubular Damage Markers in the Long-Term Period after Renal Transplantation

BACKGROUND: The primary goal of this study was to evaluate the influence of cytochrome P450 (CYP) 3A5 (6986A>G) and ABCB1 (3435C>T) polymorphisms on tacrolimus (TAC) dosage regimen and exposure. Second, we evaluated the influence of TAC dosage regimen and the tested polymorphisms on renal oxid...

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Detalhes bibliográficos
Publicado no:J Med Biochem
Main Authors: Stefanović, Nikola Z., Cvetković, Tatjana P., Veličković-Radovanović, Radmila M., Jevtović-Stoimenov, Tatjana M., Vlahović, Predrag M., Stojanović, Ivana R., Pavlović, Dušica D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Medical Biochemists of Serbia 2015
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922361/
https://ncbi.nlm.nih.gov/pubmed/28356851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/jomb-2015-0001
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