Long-Term Engraftment of ESC-Derived B-1 Progenitor Cells Supports HSC-Independent Lymphopoiesis

It is generally considered that mouse embryonic stem cell (ESC) differentiation into blood cells in vitro recapitulates yolk sac (YS) hematopoiesis. As such, similar to YS-derived B-progenitors, we demonstrate here that ESC-derived B-progenitors differentiate into B-1 and marginal zone B cells, but...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Lin, Yang, Kobayashi, Michihiro, Azevedo Portilho, Nathalia, Mishra, Akansha, Gao, Hongyu, Liu, Yunlong, Wenzel, Pamela, Davis, Brian, Yoder, Mervin C., Yoshimoto, Momoko
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409422/
https://ncbi.nlm.nih.gov/pubmed/30745034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.01.006
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