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Applications of Immunopharmacogenomics: Predicting, Preventing, and Understanding Immune-Mediated Adverse Drug Reactions

Adverse drug reactions are a significant health care burden. Immune-mediated adverse drug reactions (IM-ADRs) contribute a disproportionately high amount of that burden. Variation in human leukocyte antigen (HLA) genes has emerged as a potential pre-prescription screening strategy for the prevention...

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Dettagli Bibliografici
Pubblicato in:Annu Rev Pharmacol Toxicol
Autori principali: Karnes, Jason H, Miller, Matthew A., White, Katie D, Konvinse, Katherine, Pavlos, Rebecca, Redwood, Alec J, Peter, Jonny, Lehloenya, Ranks, Mallal, Simon, Phillips, Elizabeth J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409210/
https://ncbi.nlm.nih.gov/pubmed/30134124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010818-021818
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