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The Biguanides Metformin and Buformin in Combination with 2-Deoxy-glucose or WZB-117 Inhibit the Viability of Highly Resistant Human Lung Cancer Cells

The biguanides metformin (MET) and to a lesser extent buformin (BUF) have recently been shown to exert anticancer effects. In particular, MET targets cancer stem cells (CSCs) in a variety of cancer types but these compounds have not been extensively tested for combination therapy. In this study, we...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Yakisich, Juan Sebastian, Azad, Neelam, Kaushik, Vivek, Iyer, Anand K. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409035/
https://ncbi.nlm.nih.gov/pubmed/30918522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/6254269
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