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Exploring protein-protein interactions using the Site-Identification by Ligand Competitive Saturation (SILCS) methodology

Protein docking methods are powerful computational tools to study protein-protein interactions (PPI). While a significant number of docking algorithms have been developed, they are usually based on rigid protein models or with limited considerations of protein flexibility and the desolvation effect...

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Bibliographic Details
Published in:Proteins
Main Authors: Yu, Wenbo, Jo, Sunhwan, Lakkaraju, Sirish Kaushik, Weber, David J., MacKerell, Alexander D.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408985/
https://ncbi.nlm.nih.gov/pubmed/30582220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25650
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