Apoptotic tumor cell-derived microRNA-375 uses CD36 to alter the tumor-associated macrophage phenotype

Tumor-immune cell interactions shape the immune cell phenotype, with microRNAs (miRs) being crucial components of this crosstalk. How they are transferred and how they affect their target landscape, especially in tumor-associated macrophages (TAMs), is largely unknown. Here we report that breast can...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Frank, Ann-Christin, Ebersberger, Stefanie, Fink, Annika F., Lampe, Sebastian, Weigert, Andreas, Schmid, Tobias, Ebersberger, Ingo, Syed, Shahzad Nawaz, Brüne, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6408494/
https://ncbi.nlm.nih.gov/pubmed/30850595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-08989-2
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